Onglyza And Kombiglyze Xr Lawsuits: Three Things To Know

1.Diabetes drugs
Onglyza is composed of the active ingredient Saxagliptin and Kombiglyze XR is a combination of Saxagliptin and Metformin. Both are DPP-4 inhibitors used to treat type two diabetes. Both drugs are manufactured by AstraZeneca, formerly Bristol-Myers
Squibb Company. Onglyza was approved in the U.S. on July 31, 2009 and Kombiglyze XR was approved for sale on November 5, 2010.

2. Heart Failure
In April 2014, an FDA Advisory Committee meeting occurred regarding cardiovascular safety concerns associated with Saxagliptin. The SAVOR study (Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus; can be found here:
https://www.nejm.org/doi/full/10.1056/NEJMoa1307684#t=article) revealed a statistically significant 27 percent increased risk of heart failure in those taking Saxagliptin. The shocking results of the SAVOR study prompted the FDA to request the raw data from the SAVOR study to allow the FDA to analyze the data free from
manipulation. Subsequently, the FDA Advisory Committee recommended that Saxagliptin drugs add a warning specific to heart failure on their label. On April 5, 2016, a warning specific to heart failure was added to Saxagliptin drug labels.

3. Multidistrict Litigation in Kentucky – MDL 2809
As of January 2018, approximately 85 lawsuits related to heart failure caused by Saxagliptin were pending around the country. Because the lawsuits shared common issues, on February 2, 2018, the Judicial Panel on Multidistrict Litigation ordered all cases against the manufacturers of Onglyza and Kombiglyze XR to be transferred to the
Eastern District of Kentucky, where Judge Karen K. Caldwell would preside over the coordinated pretrial proceedings. As of February 26, 2019, just one year later, over 230 cases are currently pending before Judge Caldwell in the MDL. On September 6, 2018, Judge Caldwell appointed Jennifer A. Moore of Moore Law Group, PLLC and Timothy Clark of Sanders Phillips Grossman, LLC as plaintiffs’ co-lead counsel in MDL 2809.


Have you been injured?
If you or someone you love suffered heart failure or congestive heart failure while taking Onglyza or Kombiglyze XR, contact the lawyers at Moore Law Group, PLLC at 502-717-4080 for a free, no-obligation evaluation of your potential case.

Onglyza and Kombiglyze

Three Things To Know

1.   Diabetes drugs

Onglyza is composed of the active ingredient Saxagliptin and Kombiglyze XR is a combination of Saxagliptin and Metformin. Both are DPP-4 inhibitors used to treat type two diabetes. Both drugs are manufactured by AstraZeneca, formerly Bristol-Myers Squibb Company. Onglyza was approved in the U.S. on July 31, 2009 and Kombiglyze XR was approved for sale on November 5, 2010.

2.   Heart Failure

In April 2014, an FDA Advisory Committee meeting occurred regarding cardiovascular safety concerns associated with Saxagliptin. The SAVOR study (Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus; can be found here: https://www.nejm.org/doi/full/10.1056/NEJMoa1307684#t=article) revealed a statistically significant 27 percent increased risk of heart failure in those taking Saxagliptin. The shocking results of the SAVOR study prompted the FDA to request the raw data from the SAVOR study to allow the FDA to analyze the data free from manipulation. Subsequently, the FDA Advisory Committee recommended that Saxagliptin drugs add a warning specific to heart failure on their label.

On April 5, 2016, a warning specific to heart failure was added to Saxagliptin drug labels.

3.   Multidistrict Litigation in Kentucky – MDL 2809

As of January 2018, approximately 85 lawsuits related to heart failure caused by Saxagliptin were pending around the country. Because the lawsuits shared common issues, on February 2, 2018, the Judicial Panel on Multidistrict Litigation ordered all cases against the manufacturers of Onglyza and Kombiglyze XR to be transferred to the Eastern District of Kentucky, where Judge Karen K. Caldwell would preside over the coordinated pretrial proceedings. As of February 26, 2019, just one year later, over 230 cases are currently pending before Judge Caldwell in the MDL.

On September 6, 2018, Judge Caldwell appointed Jennifer A. Moore of Moore Law Group, PLLC and Timothy Clark of Sanders Phillips Grossman, LLC as plaintiffs’ co-lead counsel in MDL 2809.

Have you been injured?

            If you or someone you love suffered heart failure or congestive heart failure while taking Onglyza or Kombiglyze XR, contact the lawyers at Moore Law Group, PLLC at 502-717-4080 for a free, no-obligation evaluation of your potential case. 

Defective Products

Companies that manufacture automobiles, machinery, and drug products have responsibility for defective products, which cause injury. Members of our firm have handled product liability cases involving automobile crashworthiness and defective products such as seat-belts, braking systems, farm machinery, medical products, machine guarding at the workplace, and others. Such defects may result in catastrophic injury such as death, paraplegia or severe disability. Because these cases are very costly and time consuming, our commitment to them is a major endeavor. Due to the short statutes of limitations in Kentucky and some other states, it is best to hire an attorney soon after an injury, so there is adequate time to investigate. Contact our firm to discuss the details of your case today. 

Moore Law Group have represented consumers who have been seriously injured due to defective design or manufacture of products. If you or a family member have been seriously injured due to the defective design or manufacture of any of the products listed below, contact the attorneys at Moore Law Group, PLLC:

  • 3M™ Combat Arms™ Earplugs
  • Allergan BIOCELL® Textured Breast Implants and Tissue Expanders
  • Essure®
  • Hernia Mesh
  • Hip replacements/Metal-on-metal hip implants
  • IVC filter
  • Roundup
  • Talc powder
  • Drugs

If you believe you or a loved one has been injured due to a defective product, call an attorney immediately. The attorneys at Moore Law Group know that your products liability case can be won or lost in the early days following your injury. That is why it is important to call an attorney immediately.  We will then secure the evidence and will notify the other side to preserve the evidence. We will fight to make sure the other side does not destroy the evidence.

As your attorney, we know what it takes to prove that a manufacturer, assembler, supplier, laboratory, distributor, retailer, or repairer is liable for a defective product. We work with experts, including engineers and designers, who are familiar with proper design and manufacturing processes. These experts inspect the product and conduct testing on exemplars. 

All of us expect the products we buy to be safe and provide adequate warnings. Although safety standards have improved over the years, defective products are still being part into the marketplace. If you are the victim of a defective product and may have a products liability case, contact us. Injuries can result from defective design, improper warning labels, and failures during the manufacturing process.